CD19 anticorps (PE)
Aperçu rapide pour CD19 anticorps (PE) (ABIN2567314)
Antigène
Voir toutes CD19 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The 1D3 monoclonal antibody specifically reacts with mouse CD19, a 95 kDa transmembrane glycoprotein, a member of the Ig superfamily and a B cell-lineage differentiation antigen expressed by all the B lymphocyte development stages, except for the terminally differentiated plasma cells.
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Purification
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Isotype
- IgG2a kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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Stock
- 4 °C
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Stockage commentaire
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- CD19 (CD19 Molecule (CD19))
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Autre désignation
- CD19
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Sujet
- The 1D3 monoclonal antibody specifically reacts with mouse CD19, a 95 kDa transmembrane glycoprotein, a member of the Ig superfamily and a B cell-lineage differentiation antigen expressed by all the B lymphocyte development stages, except for the terminally differentiated plasma cells. CD19 associates with CD21, CD81 and MHC class II to form a multi-molecular complex that initiates the mature B lymphocyte activation by interaction with the B-cell receptors. CD 19 enhances the B cell proliferation, development and activation, and the maturation of memory B cells. In CD19-deficient mice, the generation and maturation of B lymphocytes in the bone marrow and periphery are affected.
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ID gène
- 12478
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UniProt
- P25918
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Pathways
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Antigène
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